Engineering hydrogel nanoparticles to enhance transdermal local anaesthetic delivery in human eyelid skin
dc.authorid | Thanh, Nguy?n Thi Kim / 0000-0002-4131-5952 | |
dc.authorid | 0000-0003-1535-4381 | |
dc.authorid | 0000-0002-4131-5952 | |
dc.authorscopusid | 37112868500 | |
dc.authorscopusid | 56355181500 | |
dc.authorscopusid | 12779593000 | |
dc.authorscopusid | 7005152034 | |
dc.contributor.author | Özkahraman, Bengi | |
dc.contributor.author | Emeriewen, Krisztina | |
dc.contributor.author | Saleh, George Michael | |
dc.contributor.author | Thanh, Nguy?n Thi Kim | |
dc.date.accessioned | 2020-02-13T10:51:09Z | |
dc.date.available | 2020-02-13T10:51:09Z | |
dc.date.issued | 2020 | en_US |
dc.department | Hitit Üniversitesi, Mühendislik Fakültesi, Polimer Malzeme Mühendisliği Bölümü | |
dc.description.abstract | Herein, we focused on developing the feasibility of nano-enabled local anaesthetic (LA) delivery to anaesthetise the full thickness of eyelid skin. For this purpose a temperature-responsive hydrogel poly(Nvinylcaprolactam-co-hyaluronic acid) (p(VCL-co-HA)) was prepared through aqueous emulsion polymerization with a Food and Drug Administration (FDA) approved p(VCL) and hyaluronic acid (HA) showing remarkably high LA drug loading capacity. | |
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dc.description.provenance | Made available in DSpace on 2020-02-13T10:51:09Z (GMT). No. of bitstreams: 2 bengi-ozkahraman2020.pdf: 542489 bytes, checksum: 437cb16750d97ec290a69c3c848c1b35 (MD5) license_rdf: 1030 bytes, checksum: 016d5c38d05c8fdbfdbc3c4d500be754 (MD5) Previous issue date: 2020 | en |
dc.identifier.citation | Ozkahraman, B., Emeriewen, K., Saleh, G. M., Thanh, N. T. K. (2020). Engineering hydrogel nanoparticles to enhance transdermal local anaesthetic delivery in human eyelid skin. RSC Advances, 10(7), 3926-3930. | |
dc.identifier.doi | 10.1039/c9ra06712d | |
dc.identifier.endpage | 3930 | en_US |
dc.identifier.issn | 2046-2069 | |
dc.identifier.issue | 7 | en_US |
dc.identifier.scopus | 2-s2.0-85078705486 | |
dc.identifier.scopusquality | Q1 | |
dc.identifier.startpage | 3926 | en_US |
dc.identifier.uri | https://doi.org/10.1039/c9ra06712d | |
dc.identifier.uri | https://hdl.handle.net/11491/5735 | |
dc.identifier.volume | 10 | en_US |
dc.identifier.wos | WOS:000509900800035 | |
dc.identifier.wosquality | Q2 | |
dc.indekslendigikaynak | Web of Science | |
dc.indekslendigikaynak | Scopus | |
dc.institutionauthor | Özkahraman, Bengi | |
dc.language.iso | en | |
dc.publisher | Royal Society of Chemistry | |
dc.relation.ispartof | RSC Advances | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.title | Engineering hydrogel nanoparticles to enhance transdermal local anaesthetic delivery in human eyelid skin | |
dc.type | Article |