Engineering hydrogel nanoparticles to enhance transdermal local anaesthetic delivery in human eyelid skin

dc.authoridThanh, Nguy?n Thi Kim / 0000-0002-4131-5952
dc.authorid0000-0003-1535-4381
dc.authorid0000-0002-4131-5952
dc.authorscopusid37112868500
dc.authorscopusid56355181500
dc.authorscopusid12779593000
dc.authorscopusid7005152034
dc.contributor.authorÖzkahraman, Bengi
dc.contributor.authorEmeriewen, Krisztina
dc.contributor.authorSaleh, George Michael
dc.contributor.authorThanh, Nguy?n Thi Kim
dc.date.accessioned2020-02-13T10:51:09Z
dc.date.available2020-02-13T10:51:09Z
dc.date.issued2020en_US
dc.departmentHitit Üniversitesi, Mühendislik Fakültesi, Polimer Malzeme Mühendisliği Bölümü
dc.description.abstractHerein, we focused on developing the feasibility of nano-enabled local anaesthetic (LA) delivery to anaesthetise the full thickness of eyelid skin. For this purpose a temperature-responsive hydrogel poly(Nvinylcaprolactam-co-hyaluronic acid) (p(VCL-co-HA)) was prepared through aqueous emulsion polymerization with a Food and Drug Administration (FDA) approved p(VCL) and hyaluronic acid (HA) showing remarkably high LA drug loading capacity.
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dc.description.provenanceMade available in DSpace on 2020-02-13T10:51:09Z (GMT). No. of bitstreams: 2 bengi-ozkahraman2020.pdf: 542489 bytes, checksum: 437cb16750d97ec290a69c3c848c1b35 (MD5) license_rdf: 1030 bytes, checksum: 016d5c38d05c8fdbfdbc3c4d500be754 (MD5) Previous issue date: 2020en
dc.identifier.citationOzkahraman, B., Emeriewen, K., Saleh, G. M., Thanh, N. T. K. (2020). Engineering hydrogel nanoparticles to enhance transdermal local anaesthetic delivery in human eyelid skin. RSC Advances, 10(7), 3926-3930.
dc.identifier.doi10.1039/c9ra06712d
dc.identifier.endpage3930en_US
dc.identifier.issn2046-2069
dc.identifier.issue7en_US
dc.identifier.scopus2-s2.0-85078705486
dc.identifier.scopusqualityQ1
dc.identifier.startpage3926en_US
dc.identifier.urihttps://doi.org/10.1039/c9ra06712d
dc.identifier.urihttps://hdl.handle.net/11491/5735
dc.identifier.volume10en_US
dc.identifier.wosWOS:000509900800035
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorÖzkahraman, Bengi
dc.language.isoen
dc.publisherRoyal Society of Chemistry
dc.relation.ispartofRSC Advances
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleEngineering hydrogel nanoparticles to enhance transdermal local anaesthetic delivery in human eyelid skin
dc.typeArticle

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