Assessment of pineal gland volume and calcification in healthy subjects: Is it related to aging?

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dc.contributor.authorBeker Acay, Mehtap
dc.contributor.authorTuramanlar, Ozan
dc.contributor.authorHorata, Erdal
dc.contributor.authorÜnlü, Ebru
dc.contributor.authorFidan, Nurdan
dc.contributor.authorOruç, Serdar
dc.date.accessioned2019-05-13T09:07:08Z
dc.date.available2019-05-13T09:07:08Z
dc.date.issued2016
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractPurpose: The human pineal gland is a small neuroendocrine organ which produces melatonin. The main goal of this study was to provide a reference range for pineal volume in all age groups and to determine calcified and noncalcified tissue and their proportions, which may be a reflection of melatonin production in all age groups, by using very thin computerized tomography (CT) slices. Materials and methods: A total of 167 outpatients had undergone cranial CT. Each of the subject's total pineal volume (TPV), calcified pineal volume (CPV) and noncalcified pineal volume (NPV) according to age groups were calculated in cubic millimeters. Also, proportion of calcification (POC) was noted. Results: The median values were 88.5 mm3 (12.3 mm3-411mm3) for TPV, 74.3 mm3 (12.3 mm3-298 mm3) for NPV, and 3.9 mm3 (0 mm3-141 mm3) for CPV. POC showed a gradual increase from 0-49 years. In the ? 70 group, when compared with the 60-69 age group, CPV and POC values were significantly lower (P: 0.036, P: 0.034, respectively). Conclusion: This study brings a radiological point of view to the distribution of pineal calcification according to age that has a link with melatonin secretion. © 2016 The Author(s).
dc.identifier.citationBeker Açay, M., Turamanlar, O., Horata, E., Ünlü, E., Fidan, N., Oruç, S. (2016). Assessment of pineal gland volume and calcification in healthy subjects: Is it related to aging? Journal of the Belgian Society of Radiology, 100(1), 13.
dc.identifier.doi10.5334/jbr-btr.892
dc.identifier.issn1780-2393
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ4
dc.identifier.urihttps://doi.org/10.5334/jbr-btr.892
dc.identifier.urihttps://hdl.handle.net/11491/1730
dc.identifier.volume100en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherUbiquity Press
dc.relation.ispartofJournal of the Belgian Society of Radiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution 4.0 International (CC BY 4.0)*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectAgingen_US
dc.subjectCalcificationen_US
dc.subjectComputerized Tomographyen_US
dc.subjectPineal Glanden_US
dc.titleAssessment of pineal gland volume and calcification in healthy subjects: Is it related to aging?
dc.typeArticle

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