Efficient polymeric material for separation of human hemoglobin
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Tarih
2017
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor and Francis Ltd.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, negatively charged acrylic acid was used as a functional ligand to synthesise net-poly(2-hydroxyethyl methacrylate-co-acrylic acid) microparticles for the removal of hemoglobin having a positively charged Fe2+?ion in the core, as an alternative to conventional techniques to achieve a cost effective high-capacity purification. The characterization of microparticles was performed via Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, atomic force microscopy, the Brunauer – Emmett – Teller surface area analysis, and swelling test methods. Optimum adsorption conditions such as pH, initial hemoglobin concentration, temperature, and interaction time were studied batch wise. The highest adsorption capacity of microparticles was observed at pH 7.4 as 1276.4?mg hemoglobin/g polymer. The reusability of microparticles was also promising with ?5% decrease in the adsorption capacity at the end of the five adsorption-desorption cycles.
Açıklama
Anahtar Kelimeler
Acrylic Acid, Hemoglobin, Microparticles, Net-Poly(2-Hydroxyethyl Methacrylate-Co-Acrylic Acid), Separation
Kaynak
Artificial Cells, Nanomedicine and Biotechnology
WoS Q Değeri
N/A
Scopus Q Değeri
Q1
Cilt
45
Sayı
1
Künye
Erol, K., Köse, K. (2017). Efficient polymeric material for separation of human hemoglobin. Artificial Cells, Nanomedicine and Biotechnology, 45(1), 39-45.
