The effect of atropine in preventing catheter-related pain and discomfort in patients undergoing transurethral resection due to bladder tumor; prospective randomized, controlled study

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dc.authoridŞahiner, Yeliz / 0000-0002-5377-3870
dc.authoridYağan, Özgür / 0000-0003-1596-1421
dc.authorwosidDemir, Emre / AAA-8193-2020
dc.authorwosidŞahiner, Yeliz / AAR-4365-2020
dc.authorwosidYağan, Özgür / W-9943-2018
dc.contributor.authorŞahiner, Yeliz
dc.contributor.authorYağan, Özgür
dc.contributor.authorAkdağlı Ekici, Arzu
dc.contributor.authorEkici, Musa
dc.contributor.authorDemir, Emre
dc.date.accessioned2021-11-01T15:03:03Z
dc.date.available2021-11-01T15:03:03Z
dc.date.issued2020
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü
dc.description.abstractBackground: Catheter-related bladder discomfort (CRBD) has been observed in many patients undergoing a urethral catheterization. CRBD may be so severe that the patients require additional analgesics. Muscarinic receptors are involved in the mechanism of CRBD. The aim of this study is to determine the effects of the antimuscarinic properties of atropine, which is frequently used in current practice on CRBD, by comparing it with sugammadex which has no antimuscarinic effects. Methods: Sixty patients selected for transurethral resection due to bladder tumors were randomized into 2 groups: an atropine group and a sugammadex group, with no antimuscarinic effect. The patients were given rocuronium (0.6 mg/kg) as a neuromuscular-blocker. In addition to the frequency and severity of CRBD postoperatively at 0, 1, 6, 12, and 24 hours, postoperative numeric rating scale (NRS) scores, and postoperative nausea and vomiting were examined. Results: The incidence of CRBD was significantly lower in the atropine group in all postoperative measurements. The score was found to be significantly lower in the atropine group when NRS measurements were performed at all time periods (P < 0.01). There was no difference between the groups in terms of nausea and vomiting (P > 0.05). Conclusions: Atropine is a cheap, easy-to-access, safe-to-use drug for reducing CRBD symptoms, without any observed adverse effects. Since it not only reduces CRBD symptoms but also has a positive effect on postoperative pain, it can be used safely to increase patient comfort in patients receiving general anesthesia and a urinary catheter.
dc.identifier.citationŞahiner, Y., Şahiner, Y., Ekici, A. A., Ekici, M., & Demir, E. (2020). The effect of atropine in preventing catheter-related pain and discomfort in patients undergoing transurethral resection due to bladder tumor; prospective randomized, controlled study. The Korean journal of pain, 33(2), 176.
dc.identifier.doi10.3344/kjp.2020.33.2.176
dc.identifier.endpage182en_US
dc.identifier.issn2005-9159
dc.identifier.issn2093-0569
dc.identifier.issue2en_US
dc.identifier.pmid32235018
dc.identifier.scopus2-s2.0-85089625537
dc.identifier.scopusqualityQ1
dc.identifier.startpage176en_US
dc.identifier.urihttps://doi.org/10.3344/kjp.2020.33.2.176
dc.identifier.urihttps://hdl.handle.net/11491/6941
dc.identifier.volume33en_US
dc.identifier.wosWOS:000522786000010
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorDemir, Emre
dc.language.isoen
dc.publisherKorean Pain Soc
dc.relation.ispartofKorean Journal Of Pain
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAtropineen_US
dc.subjectClinical Studyen_US
dc.subjectGeneral Anesthesiaen_US
dc.subjectMuscarinic Antagonistsen_US
dc.subjectPain Measurementen_US
dc.subjectPatient Comforten_US
dc.subjectPostoperative Painen_US
dc.subjectSugammadexen_US
dc.subjectUrinary Bladder Neoplasmsen_US
dc.subjectUrinary Cathetersen_US
dc.titleThe effect of atropine in preventing catheter-related pain and discomfort in patients undergoing transurethral resection due to bladder tumor; prospective randomized, controlled study
dc.typeArticle

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