Predictors of Crimean-Congo hemorrhagic fever in the Emergency Department

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Tarih

2015

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Verduci Editore

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

OBJECTIVE: Crimean-Congo hemorrhagic fever (CCHF) is an acute illness affecting multiple organ systems characterized by thrombocytopenia, and/or leukopenia, elevated levels of alanine aminotranferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH) and creatine kinase (CK) and it has a case-fatality of 8% to 80%. In this article, we aimed to determine the clinical and laboratory findings that predicts the disease on admission. PATIENTS AND METHODS:We retrospectively analyzed the medical data of the patients admitted to our emergency department (ED) due to tick bite. These patients were divided into two groups according to their transcriptase-polymerase chain reaction (RT-PCR) test results. Findings of PCR (+) (Group 1) and PCR (-) (Group 2) patients were compared. RESULTS: Epistaxis was found to be statistically significant clinical finding in Group 1. Also, while aspartate transaminase (AST) levels and potassium (K) level were significantly higher, platelet count and white blood count (WBC) were significantly lower in Group 1 when compared to Group 2. CONCLUSIONS: Predictors of CCHF in the ED are epistaxis, leukopenia, thrombocytopenia and elevated K and AST levels. In our study, the fatality rate of CCHF was found to be 21.6%.

Açıklama

Anahtar Kelimeler

Emergency Department, Fatality Rate, Laboratory Findings, Tick Bite

Kaynak

European Review for Medical and Pharmacological Sciences

WoS Q Değeri

N/A

Scopus Q Değeri

Q2

Cilt

19

Sayı

20

Künye

Erenler, A. K., Kulaksız, F., Ülger, H., Çapraz, M., Tomak, L., Baydın, A. (2015). Predictors of Crimean-Congo hemorrhagic fever in the Emergency Department. European Review for Medical and Pharmacological Sciences, 19(20), 3811-3816.