Effect of hibernation on oxidative and antioxidant events under laboratory conditions in Anatolian ground squirrel, spermophilus xanthoprymnus (Bennett, 1835) (Mammalia: Sciuridae) from Central Anatolia

Basit Öğe Kaydı
dc.authorid0000-0003-1046-8208
dc.authorid0000-0003-0301-7775
dc.contributor.authorAvcı, Emre
dc.contributor.authorBulut, Şafak
dc.contributor.authorBircan, Filiz Sezen
dc.contributor.authorÖzlük, Aydın
dc.contributor.authorCoşkun Cevher, Şule
dc.date.accessioned2019-05-10T09:39:12Z
dc.date.available2019-05-10T09:39:12Z
dc.date.issued2014
dc.departmentHitit Üniversitesi, Fen Edebiyat Fakültesi, Moleküler Biyoloji ve Genetik Bölümü
dc.description.abstractThe oxidative stress is an integral part of the metabolic depression machinery associated with hibernation, estimations and tolerance to freezing, dehydration, hypoxia and anoxia In the present study, we aim to investigate the role of hibernation on lipid peroxidation, nitric oxide production and glutathione levels in various tissues of Anatolian Ground Squirrel Spermophilus xanthoprymnus. A total of 9 female ground squirrels were collected from different localities in Nigde, Bolkar Mountains, Turkey. All squirrels were in three different conditions: at hibernation, aroused and non-hibernation stage. They were sacrificed under anesthesia. Glutathione (GSH), reactive nitrogen oxide species (NOx) and malondialdehyde (MDA) levels were measured spectrophotometrically. GSH levels of almost all tissues were lower in the hibernating group compared with the aroused group. NOx levels were found to decrease in all tissues except the brain tissue examined on hibernating group compared to non-hibernating group. MDA levels were found to increase in brain, lungs and heart tissues examined on hibernating group compared to nonhibernating group. In conclusion, our data show that an impaired balance exists between oxidative stress and antioxidant systems in most organs and tissues during hibernation. © Copyright 2014 Zoological Society of Pakistan.
dc.identifier.citationAvci, E., Bulut, S., Bircan, F. S., Ozluk, A., & Cevher, S. C. (2014). Effect of hibernation on oxidative and antioxidant events under laboratory conditions in Anatolian Ground Squirrel, Spermophilus xanthoprymnus (Bennett, 1835)(Mammalia: Sciuridae) from Central Anatolia. Pakistan Journal of Zoology, 46(1).
dc.identifier.endpage183en_US
dc.identifier.issn0030-9923
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ4
dc.identifier.startpage177en_US
dc.identifier.urihttps://hdl.handle.net/11491/631
dc.identifier.volume46en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.relation.ispartofPakistan Journal of Zoology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAntioxidanten_US
dc.subjectHibernationen_US
dc.subjectOxidative Stressen_US
dc.subjectSpermophilus Xanthoprymnusen_US
dc.titleEffect of hibernation on oxidative and antioxidant events under laboratory conditions in Anatolian ground squirrel, spermophilus xanthoprymnus (Bennett, 1835) (Mammalia: Sciuridae) from Central Anatolia
dc.typeArticle

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
Makale Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu