Relationship between fragmented QRS complexes and ejection fraction recovery in anterior ST-segment elevation myocardial infarction patients undergoing thrombolytic treatment

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dc.contributor.authorEren, Hayati
dc.contributor.authorKaya, Ülker
dc.contributor.authorÖcal, Lütfi
dc.contributor.authorGürbüz, Ahmet Seyfeddin
dc.contributor.authorKalçık, Macit
dc.contributor.authorAbacı, Adnan
dc.date.accessioned2021-11-01T15:05:16Z
dc.date.available2021-11-01T15:05:16Z
dc.date.issued2020
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractBackground Acute anterior ST-segment elevation myocardial infarction (STEMI) is a life-threatening disease. Adverse cardiac events of acute anterior STEMI include cardiovascular death or worsening congestive heart failure. This study investigated the role of fragmented QRS complex (fQRS) in predicting insufficient ejection fraction (EF) recovery in acute anterior STEMI. Methods Patients with acute anterior STEMI who received thrombolytic therapy were prospectively enrolled in this study. Twelve-lead electrocardiography (ECG) was obtained from all patients during admission and 24 and 48 h after admission. We divided the patients into two groups according to the presence of fQRS appearance within 48 h: absence of fQRS in any lead (fQRS-), and its presence in two or more contiguous leads (fQRS+). All patients were evaluated with transthoracic echocardiography at admission, and at follow-up 6 and 12 months later. Results A total of 138 consecutive patients were included in the study. Seventy-three patients (52.9%) had fQRS in the ECG. EF recovery in the fQRS(+) group was significantly lower than that of the fQRS(-) group (39% vs. 43.9%,P< 0.001). Multiple logistic regression analysis showed that the fQRS (odds ratio: 4.147, 95% confidence interval: 1.607-10.697,P= 0.003) were an independent predictor of poor EF recovery. Conclusion The presence of fQRS is an independent predictor for inadequate EF recovery in acute anterior STEMI patients undergoing thrombolytic treatment. Assessment of fQRS on surface ECG may be used in determining high-risk patients for poor EF recovery after acute anterior STEMI.
dc.identifier.citationEren, H., Kaya, Ü., Öcal, L., Gürbüz, A. S., Kalçik, M., & Abaci, A. (2020). Relationship between fragmented QRS complexes and ejection fraction recovery in anterior ST-segment elevation myocardial infarction patients undergoing thrombolytic treatment. Coronary artery disease, 31(5), 417-423.
dc.identifier.doi10.1097/MCA.0000000000000878
dc.identifier.endpage423en_US
dc.identifier.issn0954-6928
dc.identifier.issn1473-5830
dc.identifier.issue5en_US
dc.identifier.pmid32168047
dc.identifier.scopus2-s2.0-85087533855
dc.identifier.scopusqualityQ3
dc.identifier.startpage417en_US
dc.identifier.urihttps://doi.org/10.1097/MCA.0000000000000878
dc.identifier.urihttps://hdl.handle.net/11491/7199
dc.identifier.volume31en_US
dc.identifier.wosWOS:000550694200003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKalçık, Macit
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofCoronary Artery Disease
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAnterior ST-segment Elevation Myocardial Infarctionen_US
dc.subjectEjection Fraction Recoveryen_US
dc.subjectFragmented QRSen_US
dc.titleRelationship between fragmented QRS complexes and ejection fraction recovery in anterior ST-segment elevation myocardial infarction patients undergoing thrombolytic treatment
dc.typeArticle

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