A comprehensive review of the diagnosis and management of mitral paravalvular leakage

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dc.contributor.authorGürsoy, Mustafa Ozan
dc.contributor.authorGüner, Ahmet
dc.contributor.authorKalçık, Macit
dc.contributor.authorBayam, Emrah
dc.contributor.authorÖzkan, Mehmet
dc.date.accessioned2021-11-01T15:05:14Z
dc.date.available2021-11-01T15:05:14Z
dc.date.issued2020
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractMitral paravalvular leaks (PVLs) commonly occur in patients with prosthetic valves. Paravalvular defects may be clinically inconsequential and may aggravate hemolysis or cause heart failure through regurgitation. Accordingly, patients may eventually require intervention such as redo surgery or a transcatheter closure of the defects. The introduction of purpose-specific closure devices and new steerable catheters has opened a new frontier for the transcatheter PVL closure. This mode of treatment is an initial therapy in most centers with experienced structural heart team. However, head-to-head data comparing two treatment modalities (surgery and transcatheter closure) are limited, and the world-wide experience is based on nonrandomized studies. Multimodality imaging, including three-dimensional transesophageal echocardiography, facilitates the delineation of mitral PVLs and provides essential data that aids the communication between the members of the structural heart team. In the near future, the success of interventional therapies will most probably increase in patients with mitral PVLs with the introduction of hybrid imaging modalities (echocardiography, cardiac computed tomography, and fluoroscopy). In conclusion, this paper summarizes the etiopathogenesis, clinical characteristics, diagnosis, and treatment of mitral PVLs.
dc.identifier.citationGürsoy, M. O., Güner, A., Kalçık, M., Bayam, E., & Özkan, M. (2020). A comprehensive review of the diagnosis and management of mitral paravalvular leakage. Anatolian Journal of Cardiology, 24(6), 350.
dc.identifier.doi10.14744/AnatolJCardiol.2020.10018
dc.identifier.endpage360en_US
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue6en_US
dc.identifier.pmid33253127
dc.identifier.scopus2-s2.0-85097016592
dc.identifier.scopusqualityQ3
dc.identifier.startpage350en_US
dc.identifier.urihttps://doi.org/10.14744/AnatolJCardiol.2020.10018
dc.identifier.urihttps://hdl.handle.net/11491/7188
dc.identifier.volume24en_US
dc.identifier.wosWOS:000595157500005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.institutionauthorKalçık, Macit
dc.language.isoen
dc.publisherTurkish Soc Cardiology
dc.relation.ispartofAnatolian Journal Of Cardiology
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMitral Valveen_US
dc.subjectEchocardiographyen_US
dc.subjectTranscatheter Closureen_US
dc.subjectCardiac Surgeryen_US
dc.titleA comprehensive review of the diagnosis and management of mitral paravalvular leakage
dc.typeReview Article

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