Role of Gal-3 and H-FABP in the early diagnosis of acute coronary syndrome

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dc.contributor.authorAtay, Emre
dc.contributor.authorGüzel, Mahmut Münir
dc.contributor.authorAmanvermez, Ramazan
dc.contributor.authorDemir, Muhammed Taha
dc.contributor.authorErenler, Ali Kemal
dc.contributor.authorÖzgen, Emre
dc.contributor.authorYücel, Mehmet
dc.date.accessioned2019-05-10T09:38:48Z
dc.date.available2019-05-10T09:38:48Z
dc.date.issued2019
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractOBJECTIVES: We aimed to compare the plasma levels of biomarkers such as: serum Gal-3, H-FABP, cTnI, and CK-MB in patients, who were admitted to the emergency room with chest pain, and to determine whether these biomarkers have early diagnostic value of acute coronary syndrome (ACS). METHODS: The study was performed in 60 patients aged ? 18 years, who were admitted to emergency room. These patients were divided into 3 groups: patients with STEMI (group I, n = 20), patients with NSTEMI (group II, n = 20), and patients with USAP (group III, n = 20). Serum Gal-3, H-FABP, cTnI, and CK-MB levels were measured at admission, and at the 2nd and 4th hours. RESULTS: There were statistically significant differences between the groups in terms of Gal-3 levels at admission, and the 2nd and 4th hours (p = 0.007, p = 0.002, and p = 0.001, respectively). There were statistically significant differences between the groups in terms of H-FABP levels at admission, and the 2nd and 4th hours (p = 0.001, p = 0.003, and p = 0.003, respectively).There were statistically significant differences between the groups in terms of cTnI levels at admission, and the 2nd and 4th hours (p < 0.001, p < 0.001, and p < 0.001, respectively). CONCLUSIONS: According to the results of the study, cTnI, H-FABP, and Gal-3 are useful parameters that can be used in the early diagnosis of ACS. © AEPress s.r.o.
dc.identifier.citationAtay, E., Güzel, M.M., Amanvermez, R., Demir, M.T., Erenler, A.K., Özgen, E., Yücel, M. (2019). Role of Gal-3 and H-FABP in the early diagnosis of acute coronary syndrome. Bratislavske lekarske listy, 120 (2), 124-130 .
dc.identifier.doi10.4149/BLL_2019_020
dc.identifier.endpage130en_US
dc.identifier.issn0006-9248
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpage124en_US
dc.identifier.urihttps://doi.org/10.4149/BLL_2019_020
dc.identifier.urihttps://hdl.handle.net/11491/482
dc.identifier.volume120en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherComenius University
dc.relation.ispartofBratislava Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAcute Coronary Syndromesen_US
dc.subjectEmergency Roomen_US
dc.subjectGalectin 3en_US
dc.subjectHeart-Type Fatty Acid-binding Proteinen_US
dc.titleRole of Gal-3 and H-FABP in the early diagnosis of acute coronary syndrome
dc.typeArticle

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