Is the Concentration of Cadmium, Lead, Mercury, and Selenium Related to Preterm Birth?

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dc.authorid0000-0002-3834-3864
dc.authorid0000-0001-8507-6212
dc.contributor.authorYıldırım, Engin
dc.contributor.authorDerici, Mehmet Kürşat
dc.contributor.authorDemir, Emre
dc.contributor.authorApaydın, Hakan
dc.contributor.authorKoçak, Özgür
dc.contributor.authorKan, Özgür
dc.contributor.authorGörkem, Ümit
dc.date.accessioned2019-05-10T09:39:34Z
dc.date.available2019-05-10T09:39:34Z
dc.date.issued2019
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractEnvironmental pollution and exposure of people to heavy metals cause many bad obstetric outcomes. Our aim is to demonstrate the role of cadmium (Cd), lead (Pb), mercury (Hg), and selenium (Se) in preterm labor etiology with a case-control study. In this study, between November 2017 and April 2018, preterm delivery mothers and term delivery mothers were compared in Çorum, Turkey. All deliveries were performed with cesarean sections and there were 30 mothers in the control group and 20 in the study group. The maternal blood, maternal urine, umbilical cord blood, and heavy metal levels in the amnion fluid in both groups were studied. Graphite furnace atomic absorption spectrometry was used to determine the blood concentration of Cd, Pb, Hg, and Se. We found lower levels of selenium in blood and urine of preterm delivery mothers and umbilical cord and amnion fluids of preterm infants (p < 0.01). We found a statistically significant positive correlation at selenium levels between mother’s blood and umbilical cord blood (r (50) = 0.896, p < 0.001) and between maternal urine and amniotic fluid (r (50) = 0.841, p < 0.001). We have not found a similar correlation between mother and fetus of other metals (p > 0.05). We found that selenium levels were lower in mothers who were preterm birth in the light of the data in our study. We could not determine the positive or negative correlation of Cd, Pb, and Hg levels in blood, urine, and amniotic fluid samples with preterm birth. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.
dc.identifier.citationYıldırım, E., Derici, M. K., Demir, E., Apaydın, H., Koçak, Ö., Kan, Ö., & Görkem, Ü. (2019). Is the Concentration of Cadmium, Lead, Mercury, and Selenium Related to Preterm Birth?. Biological trace element research, 1-7.
dc.identifier.doi10.1007/s12011-018-1625-2
dc.identifier.issn0163-4984
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1007/s12011-018-1625-2
dc.identifier.urihttps://hdl.handle.net/11491/728
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherHumana Press Inc.
dc.relation.ispartofBiological Trace Element Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCadmiumen_US
dc.subjectHeavy Metalen_US
dc.subjectLeaden_US
dc.subjectMercuryen_US
dc.subjectPreterm Birthen_US
dc.subjectSeleniumen_US
dc.titleIs the Concentration of Cadmium, Lead, Mercury, and Selenium Related to Preterm Birth?
dc.typeArticle

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