The Utility of CONUT Score in Indolent Lymphoma Patients

dc.contributor.authorTığlıoğlu, Mesut
dc.contributor.authorAfacan Öztürk, Hacer Berna
dc.contributor.authorYıldız, Abdulkerim
dc.contributor.authorTığlıoğlu, Pınar
dc.contributor.authorYılmaz, Fatma
dc.contributor.authorAras, Merih Reis
dc.contributor.authorAlbayrak, Meryem
dc.date.accessioned2024-02-01T11:09:04Z
dc.date.available2024-02-01T11:09:04Z
dc.date.issued2023en_US
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractBackground and Aim: Similar to the uncertainties in the treatment criteria for indolent non-Hodgkin lymphoma (iNHL), the prognostic criteria have not been fully clarified. The Controlled Nutritional Status (CONUT) score is not only used as a predictor of malnutrition but also indicates prognosis in many chronic or malignant diseases. The aim of this study is to investigate the predictive and prognostic significance of the CONUT score in patients with iNHL. Patients and Methods: A retrospective evaluation was made of 109 patients with iNHL. The CONUT scores of the patients were compared between those with an indication for treatment and those followed without treatment. The same analysis was performed between patients who developed relapse after treatment. Survival analysis was performed on all patients, and associations between survival and the CONUT score were examined. Results: The median CONUT score was found to be higher in those who had treatment indications compared to those who did not (2 vs 1; P = 0.014). In the regression model, a CONUT absolute value above 5 was found as an independent risk factor predicting relapse. In the whole study population, a CONUT absolute value >2 predicted the risk of mortality with 53.9% sensitivity and 68.7% specificity (AUC ± SE = 0.639 ± 0.07; +PV = 35%; -PV = 82.6%; P = 0.034). Conclusion: CONUT score is a predictive and prognostic factor for patients with iNHL. The development of simple, low-budget prognostic and predictive biomarkers is critical not only for determining the course of the disease but also for follow-up and treatment management.
dc.description.provenanceSubmitted by Zeynep Umut NARİN (umutarslan@hitit.edu.tr) on 2024-02-01T11:08:53Z No. of bitstreams: 1 abdulkadir-yildiz2023.pdf: 1221666 bytes, checksum: 8164138703e3f01fa38693031c072520 (MD5)en
dc.description.provenanceApproved for entry into archive by Zeynep Umut NARİN (umutarslan@hitit.edu.tr) on 2024-02-01T11:09:04Z (GMT) No. of bitstreams: 1 abdulkadir-yildiz2023.pdf: 1221666 bytes, checksum: 8164138703e3f01fa38693031c072520 (MD5)en
dc.description.provenanceMade available in DSpace on 2024-02-01T11:09:04Z (GMT). No. of bitstreams: 1 abdulkadir-yildiz2023.pdf: 1221666 bytes, checksum: 8164138703e3f01fa38693031c072520 (MD5) Previous issue date: 2023en
dc.identifier.citationTighoglu, M., Ozturk, H. B. A., Yildiz, A., Tighoglu, P., Yilmaz, F., Aras, M. R., & Albayrak, M. (2023). The Utility of CONUT Score in Indolent Lymphoma Patients. Nigerian Journal of Clinical Practice, 26(9), 1290-1296.
dc.identifier.doi10.4103/njcp.njcp_20_23
dc.identifier.issn1119-3077
dc.identifier.issn2229-7731
dc.identifier.pmid37794541
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://hdl.handle.net/11491/8781
dc.identifier.wosWOS:001098863800010
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYıldız, Abdulkerim
dc.language.isoen
dc.publisherWOLTERS KLUWER MEDKNOW PUBLICATIONS
dc.relation.ispartofNigerian Journal of Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCONUT scoreen_US
dc.subjectIndolent lymphomasen_US
dc.subjectPrognosisen_US
dc.subjectSurvivalen_US
dc.titleThe Utility of CONUT Score in Indolent Lymphoma Patients
dc.typeArticle

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