Vanishing endometrial carcinoma in hysterectomy specimens: Probable implications for fertility sparing management

Yükleniyor...
Küçük Resim

Tarih

2017

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

TUBİTAK

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Background/aim: The vanishing cancer phenomenon was first reported in radical prostatectomy specimens in the absence of neoadjuvant treatment. Reported cases are mostly well-differentiated and low-volume tumors. A similar entity was described for hysterectomy specimens of patients with biopsy proven endometrial cancer (EC). In this study, we discuss the probable reasons for vanishing EC and long-term follow-up results of EC patients without residual tumors in hysterectomy specimens. Materials and methods: This study was carried at two institutions in Ankara, Turkey, in a retrospective design. The computerized databases of both institutions were searched for endometrioid type EC patients whose final pathological specimens failed to show any residual tumor. Results: We evaluated 38 endometrial biopsy confirmed EC patients with no residual tumor detected in the hysterectomy specimens among a total of 224 women (17%) with the disease confined to the endometrium. During the follow-up period, no recurrences were noted among the patients. Conclusion: It can be suggested that premenopausal women with FIGO grade 1 endometrioid type EC with MRI proven “absent myometrial invasion” would have a significant probability of having no residual tumor after endometrial biopsy without any further medical treatment. © TÜBİTAK.

Açıklama

Anahtar Kelimeler

Endometrial Cancer, Endometrioid Type, Fertility Sparing, Residual Tumor, Vanishing Cancer

Kaynak

Turkish Journal of Medical Sciences

WoS Q Değeri

N/A

Scopus Q Değeri

Q1

Cilt

47

Sayı

6

Künye

Öz, M., Karalök, A., Şirvan, L., Taşçı, T., Öcalan, R., Turan, A. T., Güngör, T., Meydanlı, M. M. (2017). Vanishing endometrial carcinoma in hysterectomy specimens: Probable implications for fertility sparing management. Turkish Journal of Medical Sciences, 47(6), 1744-1750.