Vanishing endometrial carcinoma in hysterectomy specimens: Probable implications for fertility sparing management

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dc.contributor.authorÖz, Murat
dc.contributor.authorKaralök, Alper
dc.contributor.authorŞirvan, Levent
dc.contributor.authorTaşçı, Tolga
dc.contributor.authorÖcalan, Reyhan
dc.contributor.authorTuran, Ahmet Taner
dc.contributor.authorGüngör, Tayfun
dc.contributor.authorMeydanlı, Mehmet Mutlu
dc.date.accessioned2019-05-13T09:02:45Z
dc.date.available2019-05-13T09:02:45Z
dc.date.issued2017
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractBackground/aim: The vanishing cancer phenomenon was first reported in radical prostatectomy specimens in the absence of neoadjuvant treatment. Reported cases are mostly well-differentiated and low-volume tumors. A similar entity was described for hysterectomy specimens of patients with biopsy proven endometrial cancer (EC). In this study, we discuss the probable reasons for vanishing EC and long-term follow-up results of EC patients without residual tumors in hysterectomy specimens. Materials and methods: This study was carried at two institutions in Ankara, Turkey, in a retrospective design. The computerized databases of both institutions were searched for endometrioid type EC patients whose final pathological specimens failed to show any residual tumor. Results: We evaluated 38 endometrial biopsy confirmed EC patients with no residual tumor detected in the hysterectomy specimens among a total of 224 women (17%) with the disease confined to the endometrium. During the follow-up period, no recurrences were noted among the patients. Conclusion: It can be suggested that premenopausal women with FIGO grade 1 endometrioid type EC with MRI proven “absent myometrial invasion” would have a significant probability of having no residual tumor after endometrial biopsy without any further medical treatment. © TÜBİTAK.
dc.identifier.citationÖz, M., Karalök, A., Şirvan, L., Taşçı, T., Öcalan, R., Turan, A. T., Güngör, T., Meydanlı, M. M. (2017). Vanishing endometrial carcinoma in hysterectomy specimens: Probable implications for fertility sparing management. Turkish Journal of Medical Sciences, 47(6), 1744-1750.
dc.identifier.doi10.3906/sag-1607-93
dc.identifier.endpage1750en_US
dc.identifier.issn1300-0144
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ1
dc.identifier.startpage1744en_US
dc.identifier.urihttps://doi.org/10.3906/sag-1607-93
dc.identifier.urihttps://hdl.handle.net/11491/1323
dc.identifier.volume47en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherTUBİTAK
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectEndometrial Canceren_US
dc.subjectEndometrioid Typeen_US
dc.subjectFertility Sparingen_US
dc.subjectResidual Tumoren_US
dc.subjectVanishing Canceren_US
dc.titleVanishing endometrial carcinoma in hysterectomy specimens: Probable implications for fertility sparing management
dc.typeArticle

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