Echocardiographic measurement of epicardial adipose tissue thickness in patients with microvascular angina

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dc.authorwosidBekar, Lütfü / A-6945-2019
dc.contributor.authorKalçık, Macit
dc.contributor.authorYesin, Mahmut
dc.contributor.authorGüner, Ahmet
dc.contributor.authorBayam, Emrah
dc.contributor.authorYetim, Mücahit
dc.contributor.authorDoğan, Tolga
dc.contributor.authorKaravelioğlu, Yusuf
dc.date.accessioned2021-11-01T15:02:56Z
dc.date.available2021-11-01T15:02:56Z
dc.date.issued2019
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractIntroduction: Impaired coronary microcirculation, inflammation, and endothelial dysfunction were reported etiological factors for microvascular angina (MVA). Recently, increased epicardial adipose tissue (EAT) thickness has been associated with hypertension, metabolic syndrome, and coronary artery disease in general population. In this study, we aimed to evaluate the EAT thickness in patients with MVA. Methods: This study enrolled 200 patients (83 males; mean age: 55.4 +/- 8.2 years) who have been diagnosed with MVA and 200 controls (89 males; mean age: 54.4 +/- 8.5 years). All patients underwent transthoracic echocardiography, and EAT thickness was measured from a parasternal long-axis view as the hypoechoic space on the right ventricular free wall. Results: The mean EAT thickness was significantly higher in MVA patients than the controls (5.5 +/- 1.1 vs. 4.9 +/- 0.7 mm; p < 0.001). Multiple logistic regression analysis showed that increased EAT thickness was an independent predictor of MVA (OR = 1.183, 95% CI = 1.063-1.489; p = 0.023). In receiver operating characteristic curve analyses, EAT thickness above 5.3 mm predicted MVA with a sentivity of 68% and a specificity of 63% (AUC = 0.711, 95% CI = 0.659-0.762; p < 0.001). Conclusions: The EAT thickness was observed significantly higher in MVA patients as compared to controls. Increased EAT thickness may be associated with mechanisms that play a major role in the pathogenesis of MVA.
dc.identifier.citationKalçık, M., Yesin, M., Güner, A., Bayam, E., Yetim, M., Doğan, T., ... & Karavelioğlu, Y. (2019). Echocardiographic measurement of epicardial adipose tissue thickness in patients with microvascular angina. Interventional Medicine and Applied Science, 11(2), 106-111.
dc.identifier.doi10.1556/1646.11.2019.12
dc.identifier.endpage111en_US
dc.identifier.issn2061-1617
dc.identifier.issn2061-5094
dc.identifier.issue2en_US
dc.identifier.pmid32148914
dc.identifier.scopus2-s2.0-85071455706
dc.identifier.scopusqualityN/A
dc.identifier.startpage106en_US
dc.identifier.urihttps://doi.org/10.1556/1646.11.2019.12
dc.identifier.urihttps://hdl.handle.net/11491/6872
dc.identifier.volume11en_US
dc.identifier.wosWOS:000473624700006
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKalçık, Macit
dc.institutionauthorBekar, Lütfü
dc.institutionauthorYetim, Mücahit
dc.institutionauthorDoğan, Tolga
dc.institutionauthorKaravelioğlu, Yusuf
dc.language.isoen
dc.publisherAkademiai Kiado Zrt
dc.relation.ispartofInterventional Medicine And Applied Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCoronary Angiographyen_US
dc.subjectCoronary Artery Diseaseen_US
dc.subjectEchocardiographyen_US
dc.subjectEpicardial Adipose Tissue Thicknessen_US
dc.subjectMicrovascular Anginaen_US
dc.titleEchocardiographic measurement of epicardial adipose tissue thickness in patients with microvascular angina
dc.typeArticle

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