Non-functioning adrenal incidentalomas are associated with higher hypertension prevalence and higher risk of atherosclerosis

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dc.contributor.authorTuna, Mazhar Müslüm
dc.contributor.authorNasıroğlu İmga, Narin
dc.contributor.authorAyçiçek Doğan, Berçem
dc.contributor.authorYılmaz, Fatma Meriç
dc.contributor.authorTopçuoğlu, Canan
dc.contributor.authorAkbaba, Gülhan
dc.contributor.authorBerker, Dilek
dc.contributor.authorGüler, Serdar
dc.date.accessioned2019-05-13T08:57:31Z
dc.date.available2019-05-13T08:57:31Z
dc.date.issued2014
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractIntroduction: Adrenal incidentalomas (AIs) have been associated with an increased incidence of several cardiovascular risk factors. The aim of this study was to investigate plasma adiponectin, leptin, resistin, homocysteine, high sensitive C-reactive protein levels, and carotid intima media thickness (CIMT) in patients with non-functioning AI (NFAI). Materials and methods: This study included data from 28 patients with NFAI (Group 1) and 41 controls (Group 2). Of the patients, 50 were female and 19 were male, and the mean age was 46.7 (range 37-65) years. Results: There were no significant differences between Group 1 and 2 in terms of age, sex, or BMI. Hypertension prevalence was significantly higher in the NFAI group than in the control group (p = 0.01). Both groups had similar lipid, blood glucose, homocysteine, uric acid, high-sensitivity CRP levels. Adiponectin, leptin, and resistin levels were similar in both groups. CIMTs were significantly higher in the NFAI group. Conclusion: There is increasing evidence that several cardiometabolic risk factors occur with higher prevalence in non-functioning adrenal incidentaloma patients compared to age-matched healthy subjects. In our study, hypertension prevalence and CIMT were higher in the NFAI group. Serum adipokine levels were similar for both groups. © 2014 Italian Society of Endocrinology (SIE).
dc.identifier.citationTuna, M. M., Nasıroğlu İmga, N., Ayçiçek Doğan, B., Yılmaz, F. M., Topçuoğlu, C., Akbaba, G., Berker, D., Güler, S. (2014). Non-functioning adrenal incidentalomas are associated with higher hypertension prevalence and higher risk of atherosclerosis. Journal of Endocrinological Investigation, 37(8), 765-768.
dc.identifier.doi10.1007/s40618-014-0106-5
dc.identifier.endpage768en_US
dc.identifier.issn0391-4097
dc.identifier.issue8en_US
dc.identifier.scopusqualityQ1
dc.identifier.startpage765en_US
dc.identifier.urihttps://doi.org/10.1007/s40618-014-0106-5
dc.identifier.urihttps://hdl.handle.net/11491/945
dc.identifier.volume37en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer International Publishing
dc.relation.ispartofJournal of Endocrinological Investigation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAdipocytokineen_US
dc.subjectAdrenal Incidentalomasen_US
dc.subjectCarotid Intima-Media Thicknessen_US
dc.subjectNon-Functioning Adrenal Incidentalomaen_US
dc.titleNon-functioning adrenal incidentalomas are associated with higher hypertension prevalence and higher risk of atherosclerosis
dc.typeArticle

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