An ultrastructural study, effects of Proteus vulgaris OX19 on the rabbit spleen cells

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Tarih

2013

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Effects of Proteus vulgaris OX19 on the spleen cells of rabbits were investigated. Control group (n= 5) and Proteus treated group (n= 5) of New Zealand male rabbits were used in this study. Bacteria were injected to the rabbits in five days periods with increasing dosages for one month. Thin sections were examined by transmission electron microscope (Jeol 100CXII). Ultrastructural changes were defined in spleen tissue cells due to the antigenic stimulation of bacteria. Spleen cells observed in control group were in normal structure and cells were in close contact with each other. However, spleen cells of Proteus treated group displayed structural changes with regard to the control group in electron microscopic examinations. Chemotaxis of macrophages, forming of pseudopodia and presence of phagocytic vacuoles were observed. Lymphocytes, the major cells of spleen revealed mitotic activity. In addition, chromatin condensation in nucleus and dilatations in perinuclear space were significant. Interactions of lymphocytes and macrophages were noteworthy. © 2012 Elsevier Ltd.

Açıklama

Anahtar Kelimeler

Proteus Vulgaris, Rabbit, Spleen, Transmission Electron Microscopy

Kaynak

Micron

WoS Q Değeri

N/A

Scopus Q Değeri

Q3

Cilt

44

Sayı

1

Künye

Gül, N., Özkorkmaz, E. G., Keleşoğlu, İ., Özlük, A. (2013). An ultrastructural study, effects of Proteus vulgaris OX19 on the rabbit spleen cells. Micron, 44, 133-136.