An ultrastructural study, effects of Proteus vulgaris OX19 on the rabbit spleen cells

dc.contributor.authorGül, Nursel
dc.contributor.authorGökalp Özkorkmaz, Ebru
dc.contributor.authorKeleşoğlu, İlknur
dc.contributor.authorÖzlük, Aydın
dc.date.accessioned2019-05-13T08:58:28Z
dc.date.available2019-05-13T08:58:28Z
dc.date.issued2013
dc.departmentHitit Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji Bölümü
dc.description.abstractEffects of Proteus vulgaris OX19 on the spleen cells of rabbits were investigated. Control group (n= 5) and Proteus treated group (n= 5) of New Zealand male rabbits were used in this study. Bacteria were injected to the rabbits in five days periods with increasing dosages for one month. Thin sections were examined by transmission electron microscope (Jeol 100CXII). Ultrastructural changes were defined in spleen tissue cells due to the antigenic stimulation of bacteria. Spleen cells observed in control group were in normal structure and cells were in close contact with each other. However, spleen cells of Proteus treated group displayed structural changes with regard to the control group in electron microscopic examinations. Chemotaxis of macrophages, forming of pseudopodia and presence of phagocytic vacuoles were observed. Lymphocytes, the major cells of spleen revealed mitotic activity. In addition, chromatin condensation in nucleus and dilatations in perinuclear space were significant. Interactions of lymphocytes and macrophages were noteworthy. © 2012 Elsevier Ltd.
dc.identifier.citationGül, N., Özkorkmaz, E. G., Keleşoğlu, İ., Özlük, A. (2013). An ultrastructural study, effects of Proteus vulgaris OX19 on the rabbit spleen cells. Micron, 44, 133-136.
dc.identifier.doi10.1016/j.micron.2012.05.010
dc.identifier.endpage136en_US
dc.identifier.issn0968-4328
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ3
dc.identifier.startpage133en_US
dc.identifier.urihttps://doi.org/10.1016/j.micron.2012.05.010
dc.identifier.urihttps://hdl.handle.net/11491/1143
dc.identifier.volume44en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.relation.ispartofMicron
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectProteus Vulgarisen_US
dc.subjectRabbiten_US
dc.subjectSpleenen_US
dc.subjectTransmission Electron Microscopyen_US
dc.titleAn ultrastructural study, effects of Proteus vulgaris OX19 on the rabbit spleen cells
dc.typeArticle

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