Associations between Gilbert's syndrome and personality characteristics

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dc.authoridDüzenli, Tolga / 0000-0002-6279-1018
dc.authoridTanoğlu, Alpaslan / 0000-0002-7477-6640
dc.authoridMaden, Özgür / 0000-0002-0430-5747
dc.authorwosidDüzenli, Tolga / R-8685-2019
dc.contributor.authorDüzenli, Tolga
dc.contributor.authorMaden, Özgür
dc.contributor.authorTanoğlu, Alpaslan
dc.contributor.authorKaplan, Mustafa
dc.contributor.authorYazgan, Yusuf
dc.date.accessioned2021-11-01T15:05:30Z
dc.date.available2021-11-01T15:05:30Z
dc.date.issued2021
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractObjective: Gilbert's syndrome (GS) is a benign genetic disorder that is characterized by intermittent mild jaundice in which the liver doesn't process bilirubin properly. The aim of this study was to determine whether GS patients have a different personality structure and if there are associations between properties of temperament and character and total bilirubin levels. Methods: A total of 1665 young male individuals aged from 19 to 30 who were admitted for occupational examinations were included in this study. Careful patient history was taken, a detailed physical examination was conducted, and hematologic and biochemical tests and abdominal ultrasonography were performed. The Turkish version of the Temperament and Character Inventory (TCI) was administered to all participants. 81 patients diagnosed with GS and 150 randomly chosen healthy individuals (control group) were investigated with comparison and correlation analyses. Results: GS patients had higher scores than healthy controls for disorderliness (NS4) (p = 0.018), sentimentality (RD1) (p = 0.042), and fatigability (HA4) (p = 0.03). Moreover, Gilbert syndrome patients scored lower than controls for empathy (C2) (p = 0.041) and transpersonal identification (ST2) (p = 0.044). Bilirubin levels were positively associated with disorderliness (NS4) (r = 0.141, p = 0.032) and fatigability (HA4) (r = 0.14, p = 0.033). Conclusions: GS patients may have some different personality characteristics from healthy individuals. This study is an initial exploration of the personality structure of GS patients and the findings should be interpreted with caution. Further prospective studies are needed to identify the relationship between Gilbert disease and personality characteristics.
dc.identifier.citationDüzenli, T., Maden, Ö., Tanoğlu, A., Kaplan, M., & Yazgan, Y. (2021). Associations between Gilbert’s syndrome and personality characteristics. Trends in Psychiatry and Psychotherapy.
dc.identifier.doi10.47626/2237-6089-2020-0003
dc.identifier.endpage158en_US
dc.identifier.issn2237-6089
dc.identifier.issn2238-0019
dc.identifier.issue2en_US
dc.identifier.pmid33844900
dc.identifier.scopus2-s2.0-85114846076
dc.identifier.scopusqualityQ2
dc.identifier.startpage151en_US
dc.identifier.urihttps://doi.org/10.47626/2237-6089-2020-0003
dc.identifier.urihttps://hdl.handle.net/11491/7304
dc.identifier.volume43en_US
dc.identifier.wosWOS:000670430200010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorDüzenli, Tolga
dc.language.isoen
dc.publisherAssoc Psiquiatria Rio Grande Sul
dc.relation.ispartofTrends In Psychiatry And Psychotherapy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGilbert's Syndromeen_US
dc.subjectTemperament and Character Inventoryen_US
dc.subjectPersonality Profileen_US
dc.titleAssociations between Gilbert's syndrome and personality characteristics
dc.typeArticle

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