Presepsin:albumin ratio and C-reactive protein:albumin ratio as novel sepsis-based prognostic scores A retrospective study
[ X ]
Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer Wien
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective To investigate the prognostic value of the presepsin:albumin ratio and C-reactive protein:albumin ratio in patients with sepsis in the intensive care unit (ICU). Methods A total of 228 (129 males and 99 females) patients with newly diagnosed sepsis were included in the study. The relationship between the C-reactive protein:albumin ratio, presepsin:albumin ratio, clinicopathologic parameters, and overall survival were investigated. The associations between C-reactive protein:albumin ratio and presepsin:albumin ratio were evaluated alongside other inflammation-based prognostic scores such as quick Sepsis Related Organ Failure Assessment (qSOFA). Results The presepsin:albumin ratio was significantly higher in non-survivors (px202f;< 0.01). Patients with a high presepsin:albumin ratio had worse overall survival compared with patients with high C-reactive protein:albumin ratio levels (px202f;< 0.001). Conclusion Presepsin and presepsin:albumin ratio are markers of adverse prognosis in patients with sepsis and are superior to C-reactive protein and C-reactive protein:albumin ratio for this purpose. Presepsin:albumin ratio may be a novel marker of poor prognosis in patients with sepsis in intensive care units.
Açıklama
Anahtar Kelimeler
Albumin, C-reactive protein, Presepsin, Sepsis
Kaynak
Wiener Klinische Wochenschrift
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
132
Sayı
7-8
Künye
Kaplan, M., Duzenli, T., Tanoglu, A., Guney, B. C., Tastan, Y. O., & Bicer, H. S. (2020). Presepsin: albumin ratio and C-reactive protein: albumin ratio as novel sepsis-based prognostic scores. Wiener klinische Wochenschrift, 1-6.