Treatment of Notalgia Paresthetica with Bee Venom and Capsaicin: A pilot study with 20 patients

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dc.authorid0000-0001-8098-1686
dc.authorid0000-0002-3834-3864
dc.contributor.authorŞenel, Engin
dc.contributor.authorHolt, Shaun
dc.contributor.authorDemir, Emre
dc.date.accessioned2020-01-31T11:20:19Z
dc.date.available2020-01-31T11:20:19Z
dc.date.issued2019en_US
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractNotalgia paresthetica (NP) is a common clinical disorder characterized by hyperpigmentation, pruritus, paresthesia, and/or pain, located on the back. There is no effective treatment for patients with NP. We investigated the efficacy of a product containing bee venom (0.04%) and capsaicin (0.025%) for treating NP. Twenty patients (10 men and 10 women) with NP were included in this open-label pilot study. A biopsy was performed for each patient to exclude other dermatologic diseases. The patients were asked to apply the product to the pruritic areas once daily for 2 weeks. No other product was used during the study. The Visual Analogue Scale (VAS) score was used to evaluate the efficacy of the product. VAS scores before and after treatment were statistically different (?p = 0.005). The pretreatment median of VAS score was 8 (7-10) (8.20 ± 1.03), while the median after treatment was 3 (1-7) (3.40 ± 1.71). The product containing bee venom and capsaicin is effective in treating ?NP. A double-blind and placebo-controlled study has been planned and initiated with a greater sample size.
dc.description.provenanceSubmitted by Zeynep Umut Arslan (umutarslan@hitit.edu.tr) on 2020-01-31T11:19:59Z No. of bitstreams: 0en
dc.description.provenanceApproved for entry into archive by Zeynep Umut Arslan (umutarslan@hitit.edu.tr) on 2020-01-31T11:20:19Z (GMT) No. of bitstreams: 0en
dc.description.provenanceMade available in DSpace on 2020-01-31T11:20:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2019en
dc.identifier.citationŞenel, E., Holt, S., Demir, E. (2019). Treatment of Notalgia Paresthetica with Bee Venom and Capsaicin: A pilot study with 20 patients. Skinmed, 17(6): 370-372.
dc.identifier.endpage372en_US
dc.identifier.issn1751-7125
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ4
dc.identifier.startpage370en_US
dc.identifier.urihttps://hdl.handle.net/11491/5676
dc.identifier.volume17en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherNLM (Medline)
dc.relation.ispartofSkinmed
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subject[Belirlenecek]en_US
dc.titleTreatment of Notalgia Paresthetica with Bee Venom and Capsaicin: A pilot study with 20 patients
dc.typeArticle

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