Relationship of paratracheal lymph nodes with the progression of chronic autoimmune thyroiditis: 5-year follow-up results

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dc.contributor.authorAkbaba, Gülhan
dc.contributor.authorBerker, Dilek
dc.contributor.authorIşık, Serhat
dc.contributor.authorNasıroğlu İmga, Narin
dc.contributor.authorKüçükler, Ferit Kerim
dc.contributor.authorTütüncü, Yasemin
dc.contributor.authorGüler, Serdar
dc.date.accessioned2019-05-13T09:02:46Z
dc.date.available2019-05-13T09:02:46Z
dc.date.issued2017
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractBackground/aim: To examine changes in paratracheal lymph nodes (PLNs) and the relationship with the course of the disease in patients with chronic autoimmune thyroiditis (CAT) 5 years after diagnosis. Materials and methods: A total of 169 patients with newly diagnosed CAT and 53 healthy subjects were included in the study. All patients underwent ultrasonographic (US) examinations of the thyroid, paratracheal regions, and examined thyroid function tests. Eighty-four patients who were euthyroid at baseline and who were contacted 5 years after the diagnosis were reevaluated by US and thyroid function tests. Results: The PLNs frequency was significantly higher in the CAT group than the controls (75.1 % vs. 30.1 %, P < 0.001). Among the 84 patients who were euthyroid at the time of diagnosis and were contacted again after 5 years, 15 developed hypothyroidism. Initially, PLNs were present in all patients who developed hypothyroidism and were significantly higher than in those who remained euthyroid (respectively 100% vs. 68.7%, P = 0.009). PLN presence and PLN volume in patients who were euthyroid at baseline predicted hypothyroidism at the end of 5 years. Conclusion: PLNs may be used as an indicator of disease progression. In addition, patient age and baseline TSH levels are other factors that predict the development of hypothyroidism in time. © TÜBİTAK.
dc.identifier.citationAkbaba, G., Berker, D. S., Işık, S., İmga, N. N., Küçükler, F. K., Tütüncü, Y.A., Güler, S. (2017). Relationship of paratracheal lymph nodes with the progression of chronic autoimmune thyroiditis: 5-year follow-up results. Turkish journal of medical sciences, 47(4), 1173-1179 .
dc.identifier.doi10.3906/sag-1604-83
dc.identifier.endpage1179en_US
dc.identifier.issn1300-0144
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ1
dc.identifier.startpage1173en_US
dc.identifier.urihttps://doi.org/10.3906/sag-1604-83
dc.identifier.urihttps://hdl.handle.net/11491/1325
dc.identifier.volume47en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherTurkiye Klinikleri Journal of Medical Sciences
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAntithyroid Antibodiesen_US
dc.subjectChronic Autoimmune Thyroiditisen_US
dc.subjectHypothyroidismen_US
dc.subjectParatracheal Lymph Nodesen_US
dc.subjectUltrasonographyen_US
dc.titleRelationship of paratracheal lymph nodes with the progression of chronic autoimmune thyroiditis: 5-year follow-up results
dc.typeArticle

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