Low-dose tissue plasminogen activator in the treatment of a massive pulmonary thromboembolism in a colon cancer patient treated with bevacizumab: a case report

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dc.contributor.authorŞen, Fatma
dc.contributor.authorKaravelioğlu, Yusuf
dc.contributor.authorArısoy, Arif
dc.date.accessioned2019-05-13T09:07:08Z
dc.date.available2019-05-13T09:07:08Z
dc.date.issued2014
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractThe current study describes the fibrinolytic treatment of a patient exhibiting an acute massive pulmonary thromboembolism, who was also receiving a bevacizumab-based combination regimen for metastatic colon cancer. The administration of bevacizumab has been associated with an increased risk of venous thromboembolic events and bleeding in cancer patients. However, there is insufficient data regarding the safety and activity of thrombolytic agents in cancer patients receiving bevacizumab-based therapy. In the present case, despite the increased risk of bleeding, low-dose and prolonged tissue plasminogen activator infusion was effectively and reliably applied to treat a massive pulmonary embolism, which resulted in hemodynamic instability in the patient. © 2014, Spandidos Publications. All rights reserved.
dc.identifier.citationŞen, F., Karavelioğlu, Y., Arısoy, A. (2014). Low?dose tissue plasminogen activator in the treatment of a massive pulmonary thromboembolism in a colon cancer patient treated with bevacizumab: a case report. Oncology Letters, 8(6), 2779-2781.
dc.identifier.doi10.3892/ol.2014.2568
dc.identifier.endpage2781en_US
dc.identifier.issn1792-1074
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpage2779en_US
dc.identifier.urihttps://doi.org/10.3892/ol.2014.2568
dc.identifier.urihttps://hdl.handle.net/11491/1732
dc.identifier.volume8en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpandidos Publications
dc.relation.ispartofOncology Letters
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBevacizumaben_US
dc.subjectPulmonary Thromboembolismen_US
dc.subjectTissue Plasminogen Activatoren_US
dc.titleLow-dose tissue plasminogen activator in the treatment of a massive pulmonary thromboembolism in a colon cancer patient treated with bevacizumab: a case report
dc.typeArticle

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