Ultrasonographic Assessment of Knee Cartilage Thickness in Patients with Ulcerative Colitis: Decreased Femoral Cartilage Thickness May Be an Indicator of Extraintestinal Manifestation in Patients with Mild Activity Ulcerative Colitis

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dc.authoridDüzenli, Tolga / 0000-0002-6279-1018
dc.authorwosidDüzenli, Tolga / R-8685-2019
dc.contributor.authorDüzenli, Tolga
dc.contributor.authorAta, Emre
dc.contributor.authorKösem, Murat
dc.date.accessioned2021-11-01T15:05:01Z
dc.date.available2021-11-01T15:05:01Z
dc.date.issued2020
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractObjectives Ulcerative colitis is a systemic inflammatory disease which primarily involves the gut but presented by numerous extraintestinal manifestations. The effect of ulcerative colitis on knee cartilage has not been evaluated up to the present. In the current study, we aimed to investigate the possible relationship between the presence of ulcerative colitis and femoral cartilage thickness. Design Sixty-two patients with confirmed diagnosis of ulcerative colitis and 70 healthy controls aged 18 to 50 years referred to the gastroenterology outpatient department between January 2018 and January 2019 participated in this cross-sectional study. The measurements were made by ultrasonography with the patient in a supine position and the knees in complete flexion. Demographic, clinical, endoscopic and laboratory data were collected for all the subjects. Results The groups of ulcerative colitis and control group were similar with regard to sex, mean age, weight, height, body mass index, extremity dominancy, and existence of knee pain (P > 0.05). Medial femoral condyles, intercondylar areas, and lateral femoral condyles of both right and left knees had thinner cartilage thickness in ulcerative colitis group than control group (P < 0.001). Conclusion Knee cartilage was thinner in subjects with mild activity ulcerative colitis than in healthy controls. Decreased knee cartilage thickness may be an indicator of extraintestinal manifestation in patients with mild activity ulcerative colitis. This association between ulcerative colitis and knee cartilage degeneration may be effective in early detection of possible risk factors and potential treatment strategies for both ulcerative colitis and specific subtypes of knee osteoarthritis.
dc.identifier.citationDuzenli, T., Ata, E., & Kosem, M. (2020). Ultrasonographic Assessment of Knee Cartilage Thickness in Patients with Ulcerative Colitis: Decreased Femoral Cartilage Thickness May Be an Indicator of Extraintestinal Manifestation in Patients with Mild Activity Ulcerative Colitis. Cartilage, 1947603520968204.
dc.identifier.doi10.1177/1947603520968204
dc.identifier.issn1947-6035
dc.identifier.issn1947-6043
dc.identifier.pmid33095026
dc.identifier.scopus2-s2.0-85093951974
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1177/1947603520968204
dc.identifier.urihttps://hdl.handle.net/11491/7050
dc.identifier.wosWOS:000583686700001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorDüzenli, Tolga
dc.language.isoen
dc.publisherSage Publications Inc
dc.relation.ispartofCartilage
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectUlcerative Colitisen_US
dc.subjectExtraintestinal Manifestationen_US
dc.subjectKneeen_US
dc.subjectFemoral Cartilageen_US
dc.subjectCartilage Thicknessen_US
dc.subjectUltrasonographyen_US
dc.titleUltrasonographic Assessment of Knee Cartilage Thickness in Patients with Ulcerative Colitis: Decreased Femoral Cartilage Thickness May Be an Indicator of Extraintestinal Manifestation in Patients with Mild Activity Ulcerative Colitis
dc.typeArticle

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