Presence of fragmented QRS is associated with increased epicardial adipose tissue thickness in hypertensive patients

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dc.contributor.authorBekar, Lütfü
dc.contributor.authorKalçık, Macit
dc.contributor.authorÇelik, Oğuzhan
dc.contributor.authorAlp, Çağlar
dc.contributor.authorYetim, Mücahit
dc.contributor.authorDoğan, Tolga
dc.contributor.authorEkinözü, İsmail
dc.contributor.authorKaraarslan, Osman
dc.contributor.authorÇamkıran, Volkan
dc.contributor.authorKaravelioğlu, Yusuf
dc.contributor.authorGölbaşı, Zehra
dc.date.accessioned2019-05-10T09:39:24Z
dc.date.available2019-05-10T09:39:24Z
dc.date.issued2019
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractBackground: Epicardial adipose tissue (EAT) is a cardiometabolic risk factor, and its possible relationship with hypertension has been reported previously. Fragmented QRS (fQRS) detected on electrocardiography (ECG) has been demonstrated to be a marker of myocardial fibrosis. In this study, we aimed to investigate the relationship between the thickness of EAT, and presence of fQRS in hypertensive patients. Methods: Consecutive patients who were diagnosed with hypertension were included in the study. ECG and transthoracic echocardiography (TTE) were performed to all patients. fQRS was defined as additional R ' wave or notching/splitting of S wave in two contiguous ECG leads. Thickness of EAT was measured by TTE. Results: This study enrolled 69 hypertensive patients with fQRS on ECG and 45 hypertensive patients without fQRS as the control group. Age (P =.869), and gender distribution (P =.751) were similar in both groups. Left atrial diameter (P =.012), interventricular septal thickness (P <.001), posterior wall thickness (P <.001), left ventricular ejection fraction (P =.009), left ventricular mass (P =.006), left ventricular mass ındex (P =.014), left ventricular hypertrophy (P =.003), and EAT thickness (P <.001) were found to be significantly increased in patients with fQRS. In multivariate analysis, among these variables only EAT was observed to be an independent predictor of fQRS (odds ratio:3.306 [95% confidence interval, 0.030-0.118], P =.001). Conclusion: A significant association exists between the presence of fQRS and EAT thickness in hypertensive patients. The presence of fQRS, just as EAT thickness, may be used as a cardiometabolic risk factor in hypertensive patients. © 2019 Wiley Periodicals, Inc.
dc.identifier.citationBekar, L., Kalçık, M., Çelik, O., Alp, Ç., Yetim, M., Doğan, T., ... & Gölbaşı, Z. (2019). Presence of fragmented QRS is associated with increased epicardial adipose tissue thickness in hypertensive patients. Journal of Clinical Ultrasound, 47(6), 345-350.
dc.identifier.doi10.1002/jcu.22683
dc.identifier.issn0091-2751
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.1002/jcu.22683
dc.identifier.urihttps://hdl.handle.net/11491/684
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherJohn Wiley and Sons Inc.
dc.relation.ispartofJournal of Clinical Ultrasound
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectEchocardiographyen_US
dc.subjectHypertensionen_US
dc.subjectLeft Ventricular Hypertrophyen_US
dc.subjectMyocardiumen_US
dc.titlePresence of fragmented QRS is associated with increased epicardial adipose tissue thickness in hypertensive patients
dc.typeArticle

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