The relationship between CHA2DS2VASc score and left ventricular apical thrombus formation in patients with acute anterior ST segment elevation myocardial infarction

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dc.authorid0000-0002-8791-4475
dc.contributor.authorBayam, Emrah
dc.contributor.authorÇakmak, Ender Özgün
dc.contributor.authorYıldırım, Ersin
dc.contributor.authorKalçık, Macit
dc.date.accessioned2024-01-25T07:49:42Z
dc.date.available2024-01-25T07:49:42Z
dc.date.issued2023en_US
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractBackground:Left ventricular apical thrombus(LVAT) formation is a well-known complication ofacute anterior myocardial infarction (AMI). The CHA2DS2VASc is a scoring system that has beenused to estimate the risk of thromboembolism in patients with nonvalvular atrial fibrillation.This score has also been used for other clinical conditions. The aim of this study was to investi-gate the relationship between CHA2DS2VASc score and development of LVAT in patientswith AMI.Method:The study population included 378 patients (mean age: 56.5 ±12.3 years, male: 318)presenting with AMI between January 2016 and January 2020. Primary percutaneous coronaryintervention procedure was performed in all patients. Initial echocardiogram was performedwithin 7 days of admission. All patients were evaluated with echocardiography at 3rd, 6th and12th months. Patients were divided into two groups according to the presence of LVAT onechocardiography.Results:The incidence of the LVAT was 8.5% (n¼32) during a mean follow-up time of233.1 ±66.7 days. The mean CHA2DS2VASc score was notably higher in patients with LVAT com-pared to patients in the control group (3.1 ±1.9 vs. 1.9 ± 1.2,p<0.001). In Cox regression ana-lysis, high CHA2DS2VASc score, low left ventricular ejection fraction (LVEF) and the presence ofLV apical akinesis/aneurysm were the independent predictors for LVAT formation. All of theseparameters were associated with higher cumulative incidence of LVAT formation in Kaplan-Meier analyses (p<0.001 for all).Conclusion:High CHA2DS2VASc score, low LVEF and the presence of LV apical akinesis/aneur-ysm may be used for LVAT risk prediction among patients presenting with AMI.
dc.description.provenanceSubmitted by Zeynep Umut NARİN (umutarslan@hitit.edu.tr) on 2024-01-25T07:49:32Z No. of bitstreams: 0en
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dc.identifier.citationBayam, E., Çakmak, E. Ö., Yıldırım, E., Kalçık, M., Bilen, Y., Güner, A., ... & Zehir, R. (2023). The relationship between CHA2DS2VASc score and left ventricular apical thrombus formation in patients with acute anterior ST segment elevation myocardial infarction. Acta Cardiologica, 78(1), 24-31.
dc.identifier.doi10.1080/00015385.2021.1991667
dc.identifier.issn0001-5385
dc.identifier.issn1784-973X
dc.identifier.pmid34714216
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.1080/00015385.2021.1991667
dc.identifier.urihttps://hdl.handle.net/11491/8736
dc.identifier.wosWOS:000712693900001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKalçık, Macit
dc.language.isoen
dc.publisherTAYLOR & FRANCIS LTD
dc.relation.ispartofACTA CARDIOLOGICA
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAnterior myocardialinfarctionen_US
dc.subjectLeft ventricularapical thrombusen_US
dc.subjectCHA2DS2VASc scoreen_US
dc.titleThe relationship between CHA2DS2VASc score and left ventricular apical thrombus formation in patients with acute anterior ST segment elevation myocardial infarction
dc.typeArticle

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