In vivo confocal microscopy and biomicroscopy of filtering blebs after trabeculectomy
[ X ]
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Lippincott Williams and Wilkins
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose: The aim of this study is to analyze filtering blebs (FBs) after trabeculectomy with in vivo confocal microscopy (IVCM) and slit-lamp biomicroscopy. Materials and Methods: IVCM using the Heidelberg Retina Tomograph/Rostock Cornea Module and biomicroscopic examination were performed in 67 FBs in 55 patients 3 months to 30 years postoperatively (mean, 3.2±2.1 y). Although the blebs were evaluated by slit-lamp biomicroscopy, standardized FB classi-fication was used. Results: Of the patients, 9 were female (16.3%) and 46 were male (83.7%), ranging in age from 32 to 81 (51.5±13.2) years. The absence of vascularization and tortuous vessels and the presence of epithelial microcysts on the bleb were significantly correlated with good bleb function (P=0.001). IVCM findings significantly correlated with good bleb function, including the number of epithelial microcysts (P=0.002), the stromal cysts without capsule (P<0.001), minimal vascularization (P=0.002), and the absence of tortuous conjunctival vessels (P=0.003) and reticular and trabecular bleb patterns (P=0.01 and <0.01, respectively). In contrast, a hyperreflective condensed bleb stroma was significantly associated with bleb failure (P<0.001). Conclusions: IVCM supports biomicroscopic evaluation as the mainstay for FB analysis and permits diagnostic imaging of FBs to evaluate and follow-up the bleb, differentiation between good and insufficient bleb function, and a microscopic analysis at a cellular level including the structural pattern of the bleb. © 2015 Wolters Kluwer Health, Inc. All rights reserved.
Açıklama
Anahtar Kelimeler
Biomicroscopy, Filtering Bleb, In Vivo Confocal Microscopy, Trabeculectomy
Kaynak
Journal of Glaucoma
WoS Q Değeri
N/A
Scopus Q Değeri
Q2
Cilt
25
Sayı
4
Künye
Çaglar, Ç., Karpuzoğlu, N., Batur, M., Yaşar, T. (2016). In vivo confocal microscopy and biomicroscopy of filtering blebs after trabeculectomy. Journal of Glaucoma, 25(4), e377-e383.
