In vivo confocal microscopy and biomicroscopy of filtering blebs after trabeculectomy

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dc.authorid0000-0003-4391-2571
dc.contributor.authorÇağlar, İsmail Çağatay
dc.contributor.authorKarpuzoğlu, Nafiz
dc.contributor.authorBatur, Muhammed
dc.contributor.authorYaşar, Tekin
dc.date.accessioned2019-05-13T08:58:56Z
dc.date.available2019-05-13T08:58:56Z
dc.date.issued2016
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractPurpose: The aim of this study is to analyze filtering blebs (FBs) after trabeculectomy with in vivo confocal microscopy (IVCM) and slit-lamp biomicroscopy. Materials and Methods: IVCM using the Heidelberg Retina Tomograph/Rostock Cornea Module and biomicroscopic examination were performed in 67 FBs in 55 patients 3 months to 30 years postoperatively (mean, 3.2±2.1 y). Although the blebs were evaluated by slit-lamp biomicroscopy, standardized FB classi-fication was used. Results: Of the patients, 9 were female (16.3%) and 46 were male (83.7%), ranging in age from 32 to 81 (51.5±13.2) years. The absence of vascularization and tortuous vessels and the presence of epithelial microcysts on the bleb were significantly correlated with good bleb function (P=0.001). IVCM findings significantly correlated with good bleb function, including the number of epithelial microcysts (P=0.002), the stromal cysts without capsule (P<0.001), minimal vascularization (P=0.002), and the absence of tortuous conjunctival vessels (P=0.003) and reticular and trabecular bleb patterns (P=0.01 and <0.01, respectively). In contrast, a hyperreflective condensed bleb stroma was significantly associated with bleb failure (P<0.001). Conclusions: IVCM supports biomicroscopic evaluation as the mainstay for FB analysis and permits diagnostic imaging of FBs to evaluate and follow-up the bleb, differentiation between good and insufficient bleb function, and a microscopic analysis at a cellular level including the structural pattern of the bleb. © 2015 Wolters Kluwer Health, Inc. All rights reserved.
dc.identifier.citationÇaglar, Ç., Karpuzoğlu, N., Batur, M., Yaşar, T. (2016). In vivo confocal microscopy and biomicroscopy of filtering blebs after trabeculectomy. Journal of Glaucoma, 25(4), e377-e383.
dc.identifier.doi10.1097/IJG.0000000000000377
dc.identifier.endpagee383en_US
dc.identifier.issn1057-0829
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpagee377en_US
dc.identifier.urihttps://doi.org/10.1097/IJG.0000000000000377
dc.identifier.urihttps://hdl.handle.net/11491/1225
dc.identifier.volume25en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams and Wilkins
dc.relation.ispartofJournal of Glaucoma
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBiomicroscopyen_US
dc.subjectFiltering Bleben_US
dc.subjectIn Vivo Confocal Microscopyen_US
dc.subjectTrabeculectomyen_US
dc.titleIn vivo confocal microscopy and biomicroscopy of filtering blebs after trabeculectomy
dc.typeArticle

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