Electrostatic adsorption of asymmetric dimethyl arginine (adma) on poly (2-hydroxyethyl methacrylate-acrylic acid) nanoparticles
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Tarih
2017
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor and Francis Inc.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Separation and purification of asymmetric dimethylarginine (ADMA) molecule, which is an important biomolecule in terms of cardiovascular diseases, is of great importance. Among the methods, the adsorption technique is of considerable demand, and as an adsorbent, the nanoparticles are widely used. In this study, an ADMA isolation was performed via a novel method. Therefore, ADMA adsorption was achieved using a poly (2-hydroxyethyl methacrylate-acrylic acid) (poly(HEMA-AA)) nanoparticles. The change in the adsorption capacity was investigated in terms of changing interaction time, initial ADMA concentration, stirring rate, temperature and ionic strength. The functional group on the polymeric nanoparticles was characterized using Fourier Transform Infrared Spectroscopy (FT-IR); the surface morphology was determined via scanning electron microscopy (SEM), transient electron microscopy (TEM) and surface area (BET) analyzes. The Elisa Spectrophotometer was used for the quantitative analysis of the ADMA molecule. The adsorption capacity of the nanoparticles was determined as 23.76 mg/g. The adsorption process was characterized according to the isotherm calculation. © 2017 Taylor & Francis Group, LLC.
Açıklama
Anahtar Kelimeler
Acrylic Acid, ADMA, Amino Acid, Isolation, Nanoparticle, Purification
Kaynak
Journal of Macromolecular Science, Part A: Pure and Applied Chemistry
WoS Q Değeri
N/A
Scopus Q Değeri
Q2
Cilt
54
Sayı
12
Künye
Erol, K., Köse, K., Avcı, E., Köse, D. A. (2017). Electrostatic adsorption of asymmetric dimethyl arginine (adma) on poly (2-hydroxyethyl methacrylate-acrylic acid) nanoparticles. Journal of Macromolecular Science, Part A, 54(12), 902-907.
