Case report: Pediatric visceral leishmaniasis caused by leishmania infantum in northern Cyprus
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Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
American Society of Tropical Medicine and Hygiene
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Visceral leishmaniasis (VL) is a vector-borne disease widespread in the Mediterranean basin, including Cyprus. During the last decades no cases were notified from northern Cyprus, but herein three cases of VL (female: 2, male: 1, median age: 24.6 months) diagnosed during their hospital admission between January 2011 and December 2012 are reported. Diagnosis was based on clinical findings; 1 ? 1/64 titer positivity of immunofluorescence antibodies, Leishmania amastigotes in Giemsa-stained slides of bone marrow, as well as molecular identification confirmed that in all three the infecting pathogen was Leishmania infantum. Fever, splenomegaly, and hepatomegaly were the typical clinical findings. First-line treatment with liposomal amphotericin B (AmBisome; intravenous, 3 mg/kg) on days 1-5, followed by the same on days 10 and 21 yielded a successful outcome with no relapse in all cases. These confirmed VL cases found within 2 years demonstrate the presence of VL on the island. Copyright © 2016 by The American Society of Tropical Medicine and Hygiene.
Açıklama
Anahtar Kelimeler
[Belirlenecek]
Kaynak
American Journal of Tropical Medicine and Hygiene
WoS Q Değeri
N/A
Scopus Q Değeri
Q1
Cilt
95
Sayı
6
Künye
Sayılı, A., Taylan Özkan, H. A., D. F. H. Schallig, H. (2016). Case report: Pediatric visceral leishmaniasis caused by leishmania infantum in northern Cyprus. American Journal of Tropical Medicine and Hygiene, 95(6), 1386-1388.