Case report: Pediatric visceral leishmaniasis caused by leishmania infantum in northern Cyprus

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dc.contributor.authorSayılı, Ayşe
dc.contributor.authorTaylan Özkan, Hikmet Ayşegül
dc.contributor.authorD. F. H. Schallig, Henk
dc.date.accessioned2019-05-10T09:38:47Z
dc.date.available2019-05-10T09:38:47Z
dc.date.issued2016
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü
dc.description.abstractVisceral leishmaniasis (VL) is a vector-borne disease widespread in the Mediterranean basin, including Cyprus. During the last decades no cases were notified from northern Cyprus, but herein three cases of VL (female: 2, male: 1, median age: 24.6 months) diagnosed during their hospital admission between January 2011 and December 2012 are reported. Diagnosis was based on clinical findings; 1 ? 1/64 titer positivity of immunofluorescence antibodies, Leishmania amastigotes in Giemsa-stained slides of bone marrow, as well as molecular identification confirmed that in all three the infecting pathogen was Leishmania infantum. Fever, splenomegaly, and hepatomegaly were the typical clinical findings. First-line treatment with liposomal amphotericin B (AmBisome; intravenous, 3 mg/kg) on days 1-5, followed by the same on days 10 and 21 yielded a successful outcome with no relapse in all cases. These confirmed VL cases found within 2 years demonstrate the presence of VL on the island. Copyright © 2016 by The American Society of Tropical Medicine and Hygiene.
dc.identifier.citationSayılı, A., Taylan Özkan, H. A., D. F. H. Schallig, H. (2016). Case report: Pediatric visceral leishmaniasis caused by leishmania infantum in northern Cyprus. American Journal of Tropical Medicine and Hygiene, 95(6), 1386-1388.
dc.identifier.doi10.4269/ajtmh.16-0511
dc.identifier.endpage1388en_US
dc.identifier.issn0002-9637
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ1
dc.identifier.startpage1386en_US
dc.identifier.urihttps://doi.org/10.4269/ajtmh.16-0511
dc.identifier.urihttps://hdl.handle.net/11491/468
dc.identifier.volume95en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAmerican Society of Tropical Medicine and Hygiene
dc.relation.ispartofAmerican Journal of Tropical Medicine and Hygiene
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subject[Belirlenecek]en_US
dc.titleCase report: Pediatric visceral leishmaniasis caused by leishmania infantum in northern Cyprus
dc.typeArticle

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