Evaluation of the potential predictors of embolism in patients with left atrial myxoma
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Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Blackwell Publishing Inc.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Introduction: Cardiac myxomas are the most common primary intracardiac tumors. Although myxomas are histologically benign, they are potentially dangerous due to potential risk of systemic and cerebral embolism. In this study, we aimed to investigate the potential predictors of embolism in patients with left atrial myxoma. Methods: This single-center retrospective study enrolled 93 patients (mean age: 52.9 ± 15.3 years, female: 70 [75.3%]) with left atrial myxomas between 2014 and 2018. The patients were classified into two groups (embolic vs nonembolic) to investigate possible predictors of embolism. Demographic, laboratory, and echocardiographic parameters were recorded into a dataset and compared between patients with and without embolism. Results: The study population was composed of 13 (14%) patients in embolic (11 cerebrovascular and 2 peripheral) and 80 (86%) patients in nonembolic group. Demographic and laboratory parameters were similar between the groups. Tumor sizes were significantly higher in the embolic group than in the nonembolic group (5.59 ± 1.08 vs 4.29 ± 0.61; P = 0.001). By multivariate analysis, increased tumor size, increased left atrial diameter, and the presence of atrial fibrillation and irregular tumor surface were identified as independent predictors of embolism. In ROC curve analyses, tumor size above 4.6 cm predicted embolism with a sensitivity of 77% and a specificity of 73% (AUC: 0.858; 95% CI: 0.752–0.964; P < 0.001). Conclusion: The presence of atrial fibrillation, irregular tumor surface, increased tumor size, and increased left atrial diameter is associated with increased risk of embolism in patients with left atrial myxoma. Early surgery should be scheduled for such patients due to increased potential for embolism. © 2019 Wiley Periodicals, Inc.
Açıklama
Anahtar Kelimeler
Cardiac Imaging, Cardiac Surgery, Echocardiography, Embolism, Left Atrial Myxoma, Transesophageal Echocardiography
Kaynak
Echocardiography
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
36
Sayı
5
Künye
Kalçık, M., Bayam, E., Güner, A., Küp, A., Kalkan, S., Yesin, M., Gürsoy, M. O., Gündüz, S. [et.al.]. (2019). Evaluation of the potential predictors of embolism in patients with left atrial myxoma. Echocardiography, 36(5), 837-843.
