Evaluation of the potential predictors of embolism in patients with left atrial myxoma

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dc.authorscopusid55694390400
dc.authorscopusid15030767400
dc.authorscopusid57190186963
dc.authorscopusid56593194700
dc.authorscopusid57194706375
dc.authorscopusid55964749700
dc.authorscopusid37033977100
dc.contributor.authorKalçık, Macit
dc.contributor.authorBayam, Emrah
dc.contributor.authorGüner, Ahmet
dc.contributor.authorKüp, Ayhan
dc.contributor.authorKalkan, Semih
dc.contributor.authorYesin, Mahmut
dc.contributor.authorGürsoy, Mustafa Ozan
dc.contributor.authorGündüz, Sabahattin
dc.contributor.authorKarakoyun, Süleyman
dc.contributor.authorÖzkan, Mehmet
dc.date.accessioned2019-05-13T08:57:46Z
dc.date.available2019-05-13T08:57:46Z
dc.date.issued2019
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractIntroduction: Cardiac myxomas are the most common primary intracardiac tumors. Although myxomas are histologically benign, they are potentially dangerous due to potential risk of systemic and cerebral embolism. In this study, we aimed to investigate the potential predictors of embolism in patients with left atrial myxoma. Methods: This single-center retrospective study enrolled 93 patients (mean age: 52.9 ± 15.3 years, female: 70 [75.3%]) with left atrial myxomas between 2014 and 2018. The patients were classified into two groups (embolic vs nonembolic) to investigate possible predictors of embolism. Demographic, laboratory, and echocardiographic parameters were recorded into a dataset and compared between patients with and without embolism. Results: The study population was composed of 13 (14%) patients in embolic (11 cerebrovascular and 2 peripheral) and 80 (86%) patients in nonembolic group. Demographic and laboratory parameters were similar between the groups. Tumor sizes were significantly higher in the embolic group than in the nonembolic group (5.59 ± 1.08 vs 4.29 ± 0.61; P = 0.001). By multivariate analysis, increased tumor size, increased left atrial diameter, and the presence of atrial fibrillation and irregular tumor surface were identified as independent predictors of embolism. In ROC curve analyses, tumor size above 4.6 cm predicted embolism with a sensitivity of 77% and a specificity of 73% (AUC: 0.858; 95% CI: 0.752–0.964; P < 0.001). Conclusion: The presence of atrial fibrillation, irregular tumor surface, increased tumor size, and increased left atrial diameter is associated with increased risk of embolism in patients with left atrial myxoma. Early surgery should be scheduled for such patients due to increased potential for embolism. © 2019 Wiley Periodicals, Inc.
dc.identifier.citationKalçık, M., Bayam, E., Güner, A., Küp, A., Kalkan, S., Yesin, M., Gürsoy, M. O., Gündüz, S. [et.al.]. (2019). Evaluation of the potential predictors of embolism in patients with left atrial myxoma. Echocardiography, 36(5), 837-843.
dc.identifier.doi10.1111/echo.14331
dc.identifier.issn0742-2822
dc.identifier.issue5
dc.identifier.pmid30934139
dc.identifier.scopus2-s2.0-85063660128
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.1111/echo.14331
dc.identifier.urihttps://hdl.handle.net/11491/1005
dc.identifier.volume36
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKalçık, Macit
dc.language.isoen
dc.publisherBlackwell Publishing Inc.
dc.relation.ispartofEchocardiography
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCardiac Imagingen_US
dc.subjectCardiac Surgeryen_US
dc.subjectEchocardiographyen_US
dc.subjectEmbolismen_US
dc.subjectLeft Atrial Myxomaen_US
dc.subjectTransesophageal Echocardiographyen_US
dc.titleEvaluation of the potential predictors of embolism in patients with left atrial myxoma
dc.typeArticle

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