Single center experience with intralesional bleomycin sclerotherapy for lymphatic malformations
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Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer Tokyo
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose: The purpose of our study was to evaluate the efficacy of percutaneous sclerotherapy using bleomycin in treatment of lymphatic malformations. Methods: Between January 2009 and January 2013, ten patients with lymphatic malformations who were admitted to the interventional radiology department were included in this retrospective study. Intralesional bleomycin was administered by percutaneous injection through 21–23 Gauge needles with a dose of 1 mg/kg body weight. Patients were clinically and radiologically assessed at baseline and followed at first and third months after treatment. Response to treatment was measured visually by using photographs and by radiological images. Symptomatic improvement was also evaluated either by patients or parents. Results: Excellent resolution was obtained visually in 80% of patients with lymphatic malformation. Significant resolution was achieved in 20% of patients. The percentage of radiographic resolution in size and the improvement in symptoms evaluated by patients or parents were similar with visual outcomes. No side effects were recorded except for fever in one patient and transient erythema in another patient. Conclusion: Intralesional bleomycin is a safe and effective treatment for patients with lymphatic malformations. © 2017, Japan Radiological Society.
Açıklama
Anahtar Kelimeler
Bleomycin, Lymphatic Malformation, Macrocystic, Sclerotherapy
Kaynak
Japanese Journal of Radiology
WoS Q Değeri
N/A
Scopus Q Değeri
Q2
Cilt
35
Sayı
10
Künye
Yılmaz, H., Yılmaz, Ö., Çamlıdağ, İ., Belet, Ü., & Akan, H. (2017). Single center experience with intralesional bleomycin sclerotherapy for lymphatic malformations. Japanese journal of radiology, 35(10), 590-596.
