Single center experience with intralesional bleomycin sclerotherapy for lymphatic malformations

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dc.authorid0000-0001-6151-1312
dc.contributor.authorYılmaz, Hakan
dc.contributor.authorYılmaz, Özlem
dc.contributor.authorÇamlıdağ, İlkay
dc.contributor.authorBelet, Ümit
dc.contributor.authorAkan, Hüseyin
dc.date.accessioned2019-05-13T09:07:13Z
dc.date.available2019-05-13T09:07:13Z
dc.date.issued2017
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractPurpose: The purpose of our study was to evaluate the efficacy of percutaneous sclerotherapy using bleomycin in treatment of lymphatic malformations. Methods: Between January 2009 and January 2013, ten patients with lymphatic malformations who were admitted to the interventional radiology department were included in this retrospective study. Intralesional bleomycin was administered by percutaneous injection through 21–23 Gauge needles with a dose of 1 mg/kg body weight. Patients were clinically and radiologically assessed at baseline and followed at first and third months after treatment. Response to treatment was measured visually by using photographs and by radiological images. Symptomatic improvement was also evaluated either by patients or parents. Results: Excellent resolution was obtained visually in 80% of patients with lymphatic malformation. Significant resolution was achieved in 20% of patients. The percentage of radiographic resolution in size and the improvement in symptoms evaluated by patients or parents were similar with visual outcomes. No side effects were recorded except for fever in one patient and transient erythema in another patient. Conclusion: Intralesional bleomycin is a safe and effective treatment for patients with lymphatic malformations. © 2017, Japan Radiological Society.
dc.identifier.citationYılmaz, H., Yılmaz, Ö., Çamlıdağ, İ., Belet, Ü., & Akan, H. (2017). Single center experience with intralesional bleomycin sclerotherapy for lymphatic malformations. Japanese journal of radiology, 35(10), 590-596.
dc.identifier.doi10.1007/s11604-017-0672-5
dc.identifier.endpage596en_US
dc.identifier.issn1867-1071
dc.identifier.issue10en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpage590en_US
dc.identifier.urihttps://doi.org/10.1007/s11604-017-0672-5
dc.identifier.urihttps://hdl.handle.net/11491/1754
dc.identifier.volume35en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer Tokyo
dc.relation.ispartofJapanese Journal of Radiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBleomycinen_US
dc.subjectLymphatic Malformationen_US
dc.subjectMacrocysticen_US
dc.subjectSclerotherapyen_US
dc.titleSingle center experience with intralesional bleomycin sclerotherapy for lymphatic malformations
dc.typeArticle

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