A multidisciplinary approach to coronavirus disease (COVID-19)
Yükleniyor...
Dosyalar
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
MDPI
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Since December 2019, humanity has faced an important global threat. Many studies have been published on the origin, structure, and mechanism of action of the SARS-CoV-2 virus and the treatment of its disease. The priority of scientists all over the world has been to direct their time to research this subject. In this review, we highlight chemical studies and therapeutic approaches to overcome COVID-19 with seven different sections. These sections are the structure and mechanism of action of SARS-CoV-2, immunotherapy and vaccine, computer-aided drug design, repurposing therapeutics for COVID-19, synthesis of new molecular structures against COVID-19, food safety/security and functional food components, and potential natural products against COVID-19. In this work, we aimed to screen all the newly synthesized compounds, repurposing chemicals covering antiviral, anti-inflammatory, antibacterial, antiparasitic, anticancer, antipsychotic, and antihistamine compounds against COVID-19. We also highlight computer-aided approaches to develop an anti-COVID-19 molecule. We explain that some phytochemicals and dietary supplements have been identified as antiviral bioproducts, which have almost been successfully tested against COVID-19. In addition, we present immunotherapy types, targets, immunotherapy and inflammation/mutations of the virus, immune response, and vaccine issues.
Açıklama
Anahtar Kelimeler
SARS-CoV-2, COVID-19, Cytokine storm, Immunotherapy, Vaccine development, In-silico research, Small drugs, Repurposing drugs, Dietary supplements, Natural products
Kaynak
Molecules
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
26
Sayı
12
Künye
Gediz Ertürk, A., Şahin, A., Batı Ay, E., Pelit, E., Bağdatlı, Kulu, İ., Gül, M., Mesci, S., Eryılmaz, S., Oba İlter, S. & Yıldırım, T. (2021). A multidisciplinary approach to coronavirus disease (COVID-19). Molecules, 26 (12), 3526.
