A multidisciplinary approach to coronavirus disease (COVID-19)

dc.contributor.authorGediz Ertürk, Aliye
dc.contributor.authorŞahin, Arzu
dc.contributor.authorBatı Ay, Ebru
dc.contributor.authorPelit, Emel
dc.contributor.authorBağdatlı, Emine
dc.contributor.authorKulu, İrem
dc.contributor.authorGül, Melek
dc.contributor.authorMesci, Seda
dc.contributor.authorEryılmaz, Serpil
dc.contributor.authorOba İlter, Şirin
dc.contributor.authorYıldırım, Tuba
dc.date.accessioned2021-11-01T15:06:11Z
dc.date.available2021-11-01T15:06:11Z
dc.date.issued2021
dc.departmentRektörlük
dc.description.abstractSince December 2019, humanity has faced an important global threat. Many studies have been published on the origin, structure, and mechanism of action of the SARS-CoV-2 virus and the treatment of its disease. The priority of scientists all over the world has been to direct their time to research this subject. In this review, we highlight chemical studies and therapeutic approaches to overcome COVID-19 with seven different sections. These sections are the structure and mechanism of action of SARS-CoV-2, immunotherapy and vaccine, computer-aided drug design, repurposing therapeutics for COVID-19, synthesis of new molecular structures against COVID-19, food safety/security and functional food components, and potential natural products against COVID-19. In this work, we aimed to screen all the newly synthesized compounds, repurposing chemicals covering antiviral, anti-inflammatory, antibacterial, antiparasitic, anticancer, antipsychotic, and antihistamine compounds against COVID-19. We also highlight computer-aided approaches to develop an anti-COVID-19 molecule. We explain that some phytochemicals and dietary supplements have been identified as antiviral bioproducts, which have almost been successfully tested against COVID-19. In addition, we present immunotherapy types, targets, immunotherapy and inflammation/mutations of the virus, immune response, and vaccine issues.
dc.description.provenanceMade available in DSpace on 2021-11-01T15:06:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2021en
dc.identifier.citationGediz Ertürk, A., Şahin, A., Batı Ay, E., Pelit, E., Bağdatlı, Kulu, İ., Gül, M., Mesci, S., Eryılmaz, S., Oba İlter, S. & Yıldırım, T. (2021). A multidisciplinary approach to coronavirus disease (COVID-19). Molecules, 26 (12), 3526.
dc.identifier.doi10.3390/molecules26123526
dc.identifier.issn1420-3049
dc.identifier.issue12en_US
dc.identifier.pmid34207756
dc.identifier.scopus2-s2.0-85108350321
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3390/molecules26123526
dc.identifier.urihttps://hdl.handle.net/11491/7512
dc.identifier.volume26en_US
dc.identifier.wosWOS:000666658300001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMDPI
dc.relation.ispartofMolecules
dc.relation.publicationcategoryDiğer Yayınlar - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.subjectSARS-CoV-2en_US
dc.subjectCOVID-19en_US
dc.subjectCytokine stormen_US
dc.subjectImmunotherapyen_US
dc.subjectVaccine developmenten_US
dc.subjectIn-silico researchen_US
dc.subjectSmall drugsen_US
dc.subjectRepurposing drugsen_US
dc.subjectDietary supplementsen_US
dc.subjectNatural productsen_US
dc.titleA multidisciplinary approach to coronavirus disease (COVID-19)
dc.typeReview Article

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